2. Autophagy Protein Tyrosine Kinase/RTK
  3. Autophagy Bcr-Abl
  4. Nilotinib hydrochloride dihydrate

Nilotinib hydrochloride dihydrate  (Synonyms: 尼罗替尼二水盐酸盐; AMN107 hydrochloride dihydrate)

目录号: HY-10159C 纯度: 99.89%
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Nilotinib (AMN107) hydrochloride dihydrate 是一种口服可用的具有抗肿瘤活性的 Bcr-Abl 酪氨酸激酶抑制，可用于慢性骨髓性白血病的研究。

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Nilotinib hydrochloride dihydrate Chemical Structure

Nilotinib hydrochloride dihydrate Chemical Structure

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规格 价格 是否有货 数量
Free Sample (0.1 - 0.2 mg)   Apply now  
25 mg ￥450
In-stock
50 mg ￥720
In-stock
100 mg ￥1150
In-stock
200 mg ￥1956
In-stock
500 mg ￥3912
In-stock
1 g   询价  
5 g   询价  

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Other Forms of Nilotinib hydrochloride dihydrate:

Nilotinib hydrochloride dihydrate 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 38 篇科研文献

Proliferation Assay
IHC

    Nilotinib hydrochloride dihydrate purchased from MCE. Usage Cited in: Oncotarget. 2018 Apr 24;9(31):22158-22183.  [Abstract]

    Primary tumors are dissected at the end of experiment and subjected to immunohistochemistry. Representative images of primary tumor sections stained with anti-PCNA (proliferation), anti-cleaved caspase 3 (apoptosis), and anti-CD31 (angiogenesis).

    Nilotinib hydrochloride dihydrate purchased from MCE. Usage Cited in: Leuk Lymphoma. 2015;56(8):2416-23.  [Abstract]

    Cell cycle analysis of HT93A cells by flow cytometry. Cells are treated with 100 nM Nilotinib and 50 ng/mL G-CSF alone or in combination for 48 h before the cell cycle is analyzed. Nilotinib treatment increases the fraction of cells in G0/G1 phase and decreased the S+G2/M-phase fraction.

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    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Nilotinib (AMN107) hydrochloride dihydrate is an orally active Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity and can be used in studies of chronic myelogenous leukaemia[1][2][3].

    分子量

    602.01

    Formula

    C28H27ClF3N7O3
    性状

    固体

    颜色

    White to off-white

    中文名称

    尼罗替尼二水盐酸盐
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    4°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    纯度 & 产品资料
    参考文献

    Nilotinib hydrochloride dihydrate 相关分类

    • 摩尔计算器

    • 稀释计算器

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    质量   浓度   体积   分子量 *
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    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Nilotinib hydrochloride dihydrateAMN107 hydrochloride dihydrate尼罗替尼二水盐酸盐AutophagyBcr-Abltyrosine kinaseantitumorInhibitorinhibitorinhibit

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