1. PI3K/Akt/mTOR
    Epigenetics
    Cell Cycle/DNA Damage
  2. PI3K
    HDAC
  3. PI3K/HDAC-IN-1

PI3K/HDAC-IN-1 

目录号: HY-128582
产品使用指南

PI3K/HDAC-IN-1 是一种有效的 (PI3K/HDAC) 双重抑制剂,高效抑制 PI3Kδ 和 HDAC1 的 IC50 值分别为 8.1 nM 和 1.4 nM。

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PI3K/HDAC-IN-1 Chemical Structure

PI3K/HDAC-IN-1 Chemical Structure

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Description

PI3K/HDAC-IN-1 is a potent dual inhibitor of PI3K/HDAC, potently inhibits PI3Kδ and HDAC1 with IC50s of 8.1 nM and 1.4 nM, respectively[1].

IC50 & Target

PI3Kα

42 nM (IC50)

PI3Kβ

101 nM (IC50)

PI3Kγ

67 nM (IC50)

PI3Kδ

8.1 nM (IC50)

HDAC1

1.4 nM (IC50)

HDAC2

3.0 nM (IC50)

HDAC6

6.6 nM (IC50)

HDAC8

18 nM (IC50)

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

428.46

Formula

C₂₂H₂₅FN₄O₄

SMILES

CC1=C2C(C(OCCCCCCC(NO)=O)=CC(C3=CC(F)=C(OC)N=C3)=C2)=NC=N1

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
PI3K/HDAC-IN-1
目录号:
HY-128582
需求量:

PI3K/HDAC-IN-1

Cat. No.: HY-128582