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  3. PNZ5

PNZ5 

目录号: HY-100696
产品使用指南

PNZ5 是一个有效的、异恶唑类的、BET 的广泛抑制剂,有着类似(+)-JQ1 的高选择性和强效作用,其对BRD4(1) 的KD 值为 5.43 nM。

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PNZ5 Chemical Structure

PNZ5 Chemical Structure

CAS No. : 1629277-36-6

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Description

PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1)[1].

IC50 & Target[1]

BRD4(1)

5.43 nM (Kd)

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

318.37

Formula

C₂₀H₁₈N₂O₂

CAS No.

1629277-36-6

SMILES

CN1C(C2=CC=C(C3=C(C)ON=C3C)C=C2[C@@]1(C4=CC=CC=C4)[H])=O

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
PNZ5
目录号:
HY-100696
需求量:

PNZ5

Cat. No.: HY-100696