1. GPCR/G Protein
  2. LPL Receptor
  3. S1PR1 modulator 1

S1PR1 modulator 1 

目录号: HY-126145
产品使用指南

S1PR1 modulator 1 是一种选择性的 S1PR1 抑制剂,pIC50 值为 7.6,对其选择性是对 S1PR 亚型 S1PR2/3/4 的 40、80 多倍。

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S1PR1 modulator 1 Chemical Structure

S1PR1 modulator 1 Chemical Structure

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Description

S1PR1 modulator 1 is a selective S1PR1 inhibitor, with a pIC50 of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4[1].

IC50 & Target

pIC50: 7.6 (S1PR1), 6 (S1PR3)[1]

In Vitro

S1PR1 modulator 1 (Compound 10a; (Z,Z)-10a) is selective at S1PR1 over S1PR3 (pIC50, 6), S1PR2 and S1PR4 (pIC50s, <5)[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

408.51

Formula

C₂₃H₂₄N₂O₃S

SMILES

CC1=CC=CC=C1N2C(/C(S/C2=N\CCC)=C/C3=CC=C(OC(C)=O)C(C)=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
S1PR1 modulator 1
目录号:
HY-126145
需求量:

S1PR1 modulator 1

Cat. No.: HY-126145