2. Anti-infection Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  3. SARS-CoV Dihydroorotate Dehydrogenase DNA/RNA Synthesis
  4. SARS-CoV-2-IN-115

SARS-CoV-2-IN-115 (Compound 3e) 是一种 SARS-CoV-2 抑制剂。SARS-CoV-2-IN-115 在感染的 Calu-3 细胞中对 SARS-CoV-2 具有强效抗病毒活性 (EC50：1.7 μM)。SARS-CoV-2-IN-115 可有效抑制人二氢乳清酸脱氢酶 (HsDHODH) 的活性(IC50：1.5 μM)。SARS-CoV-2-IN-115 可维持免疫反应，但不影响 CD4 T 细胞增殖。

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SARS-CoV-2-IN-115 Chemical Structure

SARS-CoV-2-IN-115 Chemical Structure

CAS No. : 2557232-80-9

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SARS-CoV-2-IN-115 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SARS-CoV-2-IN-115 (Compound 3e) is a SARS-CoV-2 inhibitor. SARS-CoV-2-IN-115 has potent antiviral activity against SARS-CoV-2 in infected Calu-3 cells (EC50: 1.7  μM). SARS-CoV-2-IN-115 effectively inhibits the activity of human dihydroorotate dehydrogenase (HsDHODH) (IC50: 1.5  μM). SARS-CoV-2-IN-115 preserves immune response without antiproliferative effects on CD4 T cells [1].

分子量

250.30

Formula

C16H14N2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SARS-CoV-2-IN-115 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV-2-IN-1152557232-80-9SARS-CoVDihydroorotate DehydrogenaseDNA/RNA SynthesisSARS coronavirusDHODHInhibitorsAntiviralSARS-CoV-2Human dihydroorotate dehydrogenaseHsDHODHCalu-3 cellsCD4 T cellsInhibitorinhibitorinhibit

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