1. PROTAC
    Protein Tyrosine Kinase/RTK
  2. SNIPER
    Bcr-Abl
  3. SNIPER(ABL)-020

SNIPER(ABL)-020 

目录号: HY-111872
产品使用指南

SNIPER(ABL)-020,由 Dasatinib (ABL 抑制剂) 通过 linker 与 Bestatin (cIAP1 配体) 组合而成,可有效降解 BCR-ABL 蛋白。

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SNIPER(ABL)-020 Chemical Structure

SNIPER(ABL)-020 Chemical Structure

1.  客户无需承担相应的运输费用。

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     可免费申领三个不同产品的试用装。

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Description

SNIPER(ABL)-020, conjugating Dasatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

923.52

Formula

C₄₄H₅₉ClN₁₀O₈S

SMILES

CC1=C(NC(C2=CN=C(NC3=CC(N4CCN(C(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC5=CC=CC=C5)N)=O)=O)=O)CC4)=NC(C)=N3)S2)=O)C(Cl)=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
SNIPER(ABL)-020
目录号:
HY-111872
需求量:

SNIPER(ABL)-020

Cat. No.: HY-111872