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Z433927330 

目录号: HY-126074
产品使用指南

Z433927330 是一种有效、选择性的水通道蛋白 Aquaporin-7 (AQP7) 的抑制剂,对 AQP3AQP9的抑制作用较弱,对 mAQP7,mAQP3 和 mAQP9 的 IC50 值分别为∼~0.2 µM,~0.7 µM 和 ~1.1 µM。

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Z433927330 Chemical Structure

Z433927330 Chemical Structure

CAS No. : 1005883-72-6

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Description

Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively[1].

IC50 & Target

IC50: ~0.2 µM (mAQP7), ~0.7 µM (mAQP3), ~1.1 µM (mAQP9)[1]

In Vitro

Z433927330 inhibits glycerol permeability, with an IC50 of ~0.6 µM[1].

References
Molecular Weight

364.40

Formula

C₂₀H₂₀N₄O₃

CAS No.

1005883-72-6

SMILES

O=C(OCC)C1=CC=C(NC(NCC2=CC=C(N3N=CC=C3)C=C2)=O)C=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Z433927330
目录号:
HY-126074
需求量:

Z433927330

Cat. No.: HY-126074