2. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel
  3. Cytochrome P450 Na+/K+ ATPase
  4. 17(S)-HETE

17S-HETE 是通过细胞色素 P-450 途径产生的花生四烯酸代谢物。17S-HETE 可以作为细胞色素 P450 1B1 的变构激活剂和 ATPase 抑制剂，可以诱导心脏肥大。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

17(S)-HETE Chemical Structure

17(S)-HETE Chemical Structure

CAS No. : 183509-25-3

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of 17(S)-HETE:

17(S)-HETE 相关抗体

Top Publications Citing Use of Products

查看 Cytochrome P450 亚型特异性产品:

查看所有亚型
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

17S-HETE is arachidonic acid metabolite through cytochrome P-450 pathways. 17S-HETE serves as allosteric activator of the cytochrome P450 1B1 and inhibitor of ATPase, induces cardic hypertrophy[1][2].

IC50 & Target

CYP1B1

 

体外研究
(In Vitro)

17S-HETE (5-20 μM) 通过促进 CY1B1 的活性和蛋白质水平来促进人心脏肥大的发展[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

17(S)-HETE 相关抗体:

Real Time qPCR[1]

Cell Line: AC16
Concentration: 5-20 µM
Incubation Time: 24 h
Result: Increased β/α-MHC ratio, mRNA levels of β-MHC, ANP and CYP1B1, cell surface area by 124%, 250%, 120%, 210% and 117%, respectively.

Western Blot Analysis[1]

Cell Line: AC16
Concentration: 20 µM
Incubation Time: 24 h
Result: Increased levels of CYP1B1.
体内研究
(In Vivo)

17S-HETE (1-20 μg，动脉注射) 抑制新西兰白兔的近端小管 ATP 酶活性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: New Zealand White rabbit[2]
Dosage: 1-20 μg
Administration: injection into artery
Result: Inhibited more than 70% ATPase activity at the concentration of 2 μM.
分子量

320.47

Formula

C20H32O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

17(S)-HETE 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

17(S)-HETE183509-25-3Cytochrome P450Na+/K+ ATPaseCYPsSodium potassium pumpcardiac hypertrophyAC16Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
17(S)-HETE
目录号：
HY-116050
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z