2. Apoptosis
  3. Apoptosis
  4. 27-O-(tert-Butyldimethylsilyl)withaferin A

27-O-(tert-Butyldimethylsilyl)withaferin A 

目录号: HY-N10351
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27-O-(tert-Butyldimethylsilyl)withaferin A (compound 9a) 是一种天然的茄内酯，是一种细胞凋亡 (apoptosis) 诱导剂。27-O-(tert-Butyldimethylsilyl)withaferin A 对 HeLa、A-549 和 MCF-7 人类癌细胞系以及正常 Vero 细胞具有抗增殖活性。

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27-O-(tert-Butyldimethylsilyl)withaferin A Chemical Structure

27-O-(tert-Butyldimethylsilyl)withaferin A Chemical Structure

CAS No. : 1392820-18-6

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27-O-(tert-Butyldimethylsilyl)withaferin A 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

27-O-(tert-Butyldimethylsilyl)withaferin A (compound 9a), a natural withanolide, is an apoptosis inducer. 27-O-(tert-Butyldimethylsilyl)withaferin A shows antiproliferative activity against HeLa, A-549 and MCF-7 human cancer cell lines, and against normal Vero cells[1].

体外研究
(In Vitro)

27-O-(tert-Butyldimethylsilyl)withaferin A (compound 9a; 32 μM; 4-8 hours) inhibits caspase-3 activity in HeLa cells[1].
27-O-(tert-Butyldimethylsilyl)withaferin A (48 hours) shows antiproliferative activity against HeLa, A-549, MCF-7, and Vero cells with IC50 values of 0.9 μM, 1.5 μM, 0.7 μM, and 0.7 μM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

27-O-(tert-Butyldimethylsilyl)withaferin A 相关抗体:
分子量

584.86

Formula

C34H52O6Si
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

27-O-(tert-Butyldimethylsilyl)withaferin A 相关分类

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Keywords:

27-O-(tert-Butyldimethylsilyl)withaferin A1392820-18-6Apoptosisapoptosis induceranticancer effectsantiproliferative effectcaspase-3Inhibitorinhibitorinhibit

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