2. Metabolic Enzyme/Protease Others
  3. Drug Metabolite Isotope-Labeled Compounds
  4. 3,4-Dehydro Cilostazol-d11

3,4-Dehydro Cilostazol-d11  (Synonyms: OPC-13015-d11)

目录号: HY-135910S
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摩尔计算器

3,4-Dehydro Cilostazol-d11 是氘代标记的 3,4-Dehydro Cilostazol (HY-135910)。3,4-Dehydro Cilostazol (OPC-13015) 是西洛他唑 (Cilostazol; CLZ; HY-17464) 的活性代谢产物。3,4-Dehydro Cilostazol 可用于药代动力学研究。

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3,4-Dehydro Cilostazol-d<sub>11</sub> Chemical Structure

3,4-Dehydro Cilostazol-d11 Chemical Structure

CAS No. : 1073608-13-5

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3,4-Dehydro Cilostazol-d11 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3,4-Dehydro Cilostazol-d11 is deuterated labeled 3,4-Dehydro Cilostazol (HY-135910). 3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol (CLZ; HY-17464). 3,4-Dehydro Cilostazol is used for pharmacokinetic study[1].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

3,4-Dehydro Cilostazol-d11 相关抗体:
体内研究
(In Vivo)

3,4-Dehydro Cilostazol (OPC-13015; Oral; 1 mg/kg GLZ and 10 mg/kg CLZ) has a T1/2 of 3.94 hours, a Cmax of 1.39 μM and an AUC0-24 of 4.69 μg?h/ml. The plasma concentration time profiles of GLZ, CLZ & its active metabolite DCLZ are traceable up to 24 h, 12 h and 12 h respectively by oral administration at 1 mg/kg dose of GLZ and 10 mg/kg CLZ[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

378.51

Formula

C20H14D11N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3,4-Dehydro Cilostazol-d11 相关分类

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Keywords:

3,4-Dehydro Cilostazol-d111073608-13-5OPC-13015-d11Drug MetaboliteIsotope-Labeled CompoundscilostazolpharmacokineticglipizideInhibitorinhibitorinhibit

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