2. Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  3. nAChR GABA Receptor Potassium Channel Endogenous Metabolite
  4. Cholesterol myristate

Cholesterol myristate  (Synonyms: 胆固醇肉豆蔻酸; Cholesteryl myristate; Cholesteryl tetradecanoate)

目录号: HY-N2338 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Cholesterol myristate 是中药中天然类固醇。Cholesterol myristate 与多种离子通道结合，例如 nAChR，GABAA receptor 和内向整流钾离子通道 (potassium ion channel)。

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Cholesterol myristate Chemical Structure

Cholesterol myristate Chemical Structure

CAS No. : 1989-52-2

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规格 价格 是否有货 数量
250 mg ￥600
In-stock
500 mg   询价  
1 g   询价  

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Customer Review

Other Forms of Cholesterol myristate:

Cholesterol myristate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel.

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Mesenchymal stem cells (MSCs) transfected by the Id1 promoter reporter construct, cholesterol myristate increases the activity of Id1 promoter. Cholesterol myristate inhibits the apoptosis of MSCs induced by serum-free. Cholesterol myristate increases the expression of Id1 and its target gene bcl-x/l in MSCs treated with serum-free. Moreover, noggin, a BMP antagonist, reduces the anti-apoptotic effects of cholesterol myristate[1]. Cholesterol myristate inhibits the apoptosis of PC12 cells induced in serum-free condition. Cholesterol myristate significantly increases the expression of BMP4, BMPRIA, p-Smad1/5/8, Id1 and its antiapoptotic target gene Bcl-xL in PC12 cells treated in serum-free condition[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cholesterol myristate 相关抗体:
分子量

597.01

Formula

C41H72O2
CAS 号
性状

固体

颜色

White to off-white

中文名称

胆固醇肉豆蔻酸
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
溶解性数据
In Vitro: 

Ethanol 中的溶解度 : 3.33 mg/mL (5.58 mM; 超声助溶)

H2O 中的溶解度 : < 0.1 mg/mL (insoluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.6750 mL 8.3751 mL 16.7501 mL
5 mM 0.3350 mL 1.6750 mL 3.3500 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C储存时，请在2年内使用， -20°C储存时，请在1年内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献
Cell Assay
[1]

MSCs are cultured with or without serum in 96-well plates and treated with cholesterol myristate in various concentrations (0, 30 and 300 μg/mL) for 3 days. Each sample is repeated in five independent wells and is incubated for 72 h. After incubation, 20 μL MTT (5 mg/mL) is added and the culture is incubated for a further 4 h. The culture medium is discarded and replaced with 150 μL DMSO. The absorbance at 490nm is measured[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Cholesterol myristate 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C储存时，请在2年内使用， -20°C储存时，请在1年内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 1.6750 mL 8.3751 mL 16.7501 mL 41.8753 mL
5 mM 0.3350 mL 1.6750 mL 3.3500 mL 8.3751 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cholesterol myristate1989-52-2Cholesteryl myristate Cholesteryl tetradecanoate胆固醇肉豆蔻酸nAChRGABA ReceptorPotassium ChannelEndogenous MetaboliteNicotinic acetylcholine receptorsGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorKcsAInhibitorinhibitorinhibit

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