2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Adenylosuccinic acid

Adenylosuccinic acid  (Synonyms: Adenylosuccinate; Aspartyl adenylate)

目录号: HY-127137
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摩尔计算器

Adenylosuccinic acid (Adenylosuccinate; Aspartyl adenylate) 是一种嘌呤核糖核苷单磷酸，在核苷酸循环代谢 (nucleotide cycle metabolite) 中起作用。Adenylosuccinic acid 可以通过腺苷琥珀酸裂解酶转化成富马酸。Adenylosuccinic acid 有潜力用于杜氏肌营养不良症 (DMD) 的研究。

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Adenylosuccinic acid Chemical Structure

Adenylosuccinic acid Chemical Structure

CAS No. : 19046-78-7

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Adenylosuccinic acid 的其他形式现货产品:

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Adenylosuccinic acid 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Adenylosuccinic acid (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid has the potential for the study of duchenne muscular dystrophy(DMD)[1].

IC50 & Target

Human Endogenous Metabolite

 

体内研究
(In Vivo)

Adenylosuccinic acid (oral administration; 3-3000 µg/mL; 6 weeks) significantly improves the features of murine DMD, it decreases the number of centronucleated fibres, lipid accumulation, connective tissue infiltration and Ca2+ content of mdx tibialis anterior[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57Bl/10ScSn (normal wild-type strain; Con) and C57Bl/10mdx (mdx) mice[1]
Dosage: 3 µg/mL, 30 µg/mL, 300 µg/mL, 3000 µg/mL
Administration: 3 µg/mL for 3 days and 30 µg/mL for the next 4 days, and 300 µg/mL for one week, and then 3000 µg/mL for 6 weeks
Result: Ameliorated the symptoms of murine duchenne muscular dystrophy.
分子量

463.29

Formula

C14H18N5O11P
CAS 号
Unlabeled Cas

初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Adenylosuccinic acid 相关分类

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Keywords:

Adenylosuccinic acid19046-78-7Adenylosuccinate Aspartyl adenylateEndogenous MetaboliteDuchennemusculardystrophyDMD metabolite nucleotidecycleInhibitorinhibitorinhibit

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