2. Anti-infection
  3. Antibiotic Bacterial
  4. Anhydroerythromycin A

Anhydroerythromycin A  (Synonyms: 脱水红霉素)

目录号: HY-N7454
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摩尔计算器

Anhydroerythromycin A 是大环内酯类抗生素红霉素的降解产物。Anhydroerythromycin A 是红霉素在体内外酸性水溶液中降解形成的。Anhydroerythromycin A 在体外对金黄色葡萄球菌和蜡样芽胞杆菌具有活性 (MIC 分别为12.5 和 6.25 μg/ml)。Anhydroerythromycin A 也抑制人肝微粒体中与细胞色素 P450 (CYP) 亚型 CYP3A 相关的类固醇 6β-羟化酶的活性。

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Anhydroerythromycin A Chemical Structure

Anhydroerythromycin A Chemical Structure

CAS No. : 23893-13-2

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1 mg ￥3830
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Anhydroerythromycin A 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

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  • 参考文献

生物活性

Anhydroerythromycin A is a degradation product of the macrolide antibiotic erythromycin. Anhydroerythromycin A is formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo. Anhydroerythromycin A is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 μg/ml, respectively). Anhydroerythromycin A also inhibits steroid 6β-hydroxylase activity associated with the cytochrome P450 (CYP) isoform CYP3A in human liver microsomes.

IC50 & Target

Macrolide

 

分子量

715.91

Formula

C37H65NO12
CAS 号
中文名称

红霉素EP杂质D (Anhydroerythromycin A)
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anhydroerythromycin A 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anhydroerythromycin A23893-13-2红霉素EP杂质D (Anhydroerythromycin A)AntibioticBacterialInhibitorinhibitorinhibit

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