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  4. Antiangiogenic agent 3

Antiangiogenic agent 3 (compound 3) 是抗血管生成剂。Antiangiogenic agent 3 也是人脐静脉内皮细胞 (HUVEC) 的抑制剂。Antiangiogenic agent 3 抑制 HUVEC 迁移和趋化运动。Antiangiogenic agent 3 还降低 Src、cdc42 和 MAPK 的基因表达。

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Antiangiogenic agent 3 Chemical Structure

Antiangiogenic agent 3 Chemical Structure

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Antiangiogenic agent 3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antiangiogenic agent 3 (compound 3) is a potent antiangiogenic agent. Antiangiogenic agent 3 is an inhibitor of human umbilical vein endothelial cells (HUVEC). Antiangiogenic agent 3 inhibits HUVEC migration and chemotactic motilities. Antiangiogenic agent 3 also decreases the gene expression of Src, cdc42, and MAPK[1].

体外研究
(In Vitro)

Antiangiogenic agent 3 (6.25-200 μM；48 小时) 降低人脐静脉内皮细胞 (HUVEC) 的细胞活力[1]。
Antiangiogenic agent 3 (5 μM, 10 μM; 24 h) 抑制 VEGF 诱导的 HUVEC 迁移或趋化运动，在 5 μM 和 10 μM 时抑制率分别为 30% 和 33%[1]。
Antiangiogenic agent 3 (10 μM; 24 h) 下调与上皮细胞迁移相关的Src、cdc42和MAPK基因表达[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antiangiogenic agent 3 相关抗体:

RT-PCR[1]

Cell Line: Human umbilical vein endothelial cells (HUVEC)
Concentration: 10 μM
Incubation Time: 24 hours
Result: Decreased the expressions of VEGF and some related to epithelial cell survival, such as Akt and mTOR.
Decreased the expressions of Src, cdc42, and MAPK.
分子量

360.36

Formula

C19H20O7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antiangiogenic agent 3 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Antiangiogenic agent 3Antiangiogenic agent3Antiangiogenic agent-3OthersInhibitorinhibitorinhibit

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