2. Anti-infection
  3. Bacterial Antibiotic
  4. Antibacterial agent 105

Antibacterial agent 105 (Compound 17) 是一种喹诺酮类的 Phenanthrolinic 类似物，对 M. tuberculosis 具有抗菌活性 (MIC90=2.64 μM)。Antibacterial agent 105 对多种菌种都具有抗菌活性，对M. smegmatis, M. aurum, M. marinum, BCG, E. aerogenes 和 S. aureus 的 MIC90 分别为 11.18, 11.18，0.70，1.40，44.70 和 22.35 μM。

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Antibacterial agent 105 Chemical Structure

Antibacterial agent 105 Chemical Structure

CAS No. : 2364493-24-1

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Antibacterial agent 105 相关抗体

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生物活性

Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM)。Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18，0.70，1.40，44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum,BCG, E. aerogenes and S. aureus, respectively[1].

体外研究
(In Vitro)

Antibacterial agent 105 (compound 17) has inhibitory effect on the growth of M. tuberculosis replicating in vitro cultured macrophages[1].
Antibacterial agent 105 (compound 17) (24 hours) has no toxicity on Vero cells line and human macrophages[1].
Antibacterial agent 105 (compound 17) has antibacterial activities against FQ resistant bacteria and XDR-TB[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 105 相关抗体:
分子量

299.24

Formula

C14H9N3O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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参考文献

Antibacterial agent 105 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 1052364493-24-1Antibacterial agent105Antibacterial agent-105BacterialAntibioticphenanthrolinic analogquinolonesantibacterial activityM. tuberculosisInhibitorinhibitorinhibit

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