2. Anti-infection
  3. Penicillin-binding protein (PBP) Bacterial
  4. Antibacterial agent 116

Antibacterial agent 116 是一种含二苯甲酮的水杨酰苯胺类化合物。Antibacterial agent 116 能抑制肽聚糖的形成而具有较强的抗菌活性。Antibacterial agent 116 可作为光亲和探针标记 Acinetobacter baumannii 的青霉素结合蛋白 (PBP1b)，干扰肽聚糖链的生长，阻断其增殖。

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Antibacterial agent 116 Chemical Structure

Antibacterial agent 116 Chemical Structure

CAS No. : 99330-28-6

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Antibacterial agent 116 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 116 is a benzophenone-containing salicylanilide compound. Antibacterial agent 116 has potent antibacterial activity by inhibiting the peptidoglycan formation. Antibacterial agent 116 is used as a photoaffinity probe to label Acinetobacter baumannii penicillin-binding protein (PBP1b), block the propagation pathway to disrupt the growth of peptidoglycan chain[1].

体外研究
(In Vitro)

Antibacterial agent 116 (compound 1) can photo-label A. baumannii PBP1b, targets to R367 and E372 binding site[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 116 相关抗体:
分子量

730.12

Formula

C26H15Cl2I2NO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antibacterial agent 116 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 11699330-28-6Antibacterial agent116Antibacterial agent-116Penicillin-binding protein (PBP)Bacterialantibacterial agentmolecular dockingpeptidoglycanphotoaffinity labelingsalicylanilide compoundbenzophenone-containing salicylanilide compoundpeptidoglycan chainphoto-labelInhibitorinhibitorinhibit

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