1. Anti-infection
  2. Bacterial
  3. Antibacterial agent 138

Antibacterial agent 138 对多重耐药菌具有优异的抗菌活性。Antibacterial agent 138 抑制细菌蛋白质合成和细菌细胞壁。

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Antibacterial agent 138 Chemical Structure

Antibacterial agent 138 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 138 has excellent antibacterial activity to multi-drug resistant bacteria. Antibacterial agent 138 inhibits bacterial protein synthesis but bacterial cell walls[1].

体外研究
(In Vitro)

Antibacterial agent 138 (化合物 e4) (0.063 μg/mL,24 h) 对 MRSA 和 MRSE 表现出优异的抑制作用[1]
Antibacterial agent 138 对多重耐药菌具有抗菌活性,MICs (0.063-32μg/mL) 比泰妙菌素低 16-64 倍[1]
Antibacterial agent 138 (60 μg/mL, 24 h) 在 HEPG2 和 HEK293 细胞中未显示出细胞毒性迹象[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: S. aureus, MRSA, S. pneumonia, MRSE, B. subtilis, VRE, K. peneumoniae.
Concentration: 0-50 μg/mL approximately.
Incubation Time: 24 h
Result: MICs: 0.063, 0.063, <0.031, 0.063, 4, 4, 2 μg/mL
体内研究
(In Vivo)

Antibacterial agent 138 (化合物 e4) (2.5-40 mg/kg,i.p.) 在全身多药耐药金黄色葡萄球菌感染小鼠模型中显示出抗菌活性[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice model of systemic multi-drug resistant S. aureus infection[1]
Dosage: 2.5, 5, 10, 20, 40 mg/kg
Administration: i.p.
Result: Prolonged survival rate.
Reduced bacterial loads in the lungs and liver of infected mice.
分子量

697.75

Formula

C34H52INO4S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Antibacterial agent 138 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Antibacterial agent 138
目录号:
HY-149089
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