2. Anti-infection
  3. Bacterial
  4. Antimicrobial agent-6

Antimicrobial agent-6 (Compound 11) 是一种抗菌剂 (antimicrobial)，对革兰氏阳性和革兰氏阴性细菌的 MIC 范围为 4-8 μg/mL。Antimicrobial agent-6 也具有抗炎活性。

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Antimicrobial agent-6 Chemical Structure

Antimicrobial agent-6 Chemical Structure

CAS No. : 2978694-10-7

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Antimicrobial agent-6 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antimicrobial agent-6 (Compound 11) is an antimicrobial agent with a MIC range of 4-8 μg/mL against gram-positive and gram-negative bacteria. Antimicrobial agent-6 also shows anti-inflammatory activity[1].

体外研究
(In Vitro)

Antimicrobial agent-6 (Compound 11) (0-256 μg/mL; 18-24 h) shows antibacterial activity with geometric mean (GM) values of the MICs of 5 μg/mL[1].
Antimicrobial agent-6 shows minimum hemolytic concentration (MHC) of >256 μg/mL, the therapeutic index is 102.4[1].
Antimicrobial agent-6 (5 or 20 μg/mL; 18 h) effectively inhibits the release and expression of NO and TNF-α from LPS-stimulated RAW 264.7 cells[1].
Antimicrobial agent-6 is resistant to various physiological salts, human serum, and proteases[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antimicrobial agent-6 相关抗体:

Cell Viability Assay[1]

Cell Line: E. coli [KCTC 1682], P. aeruginosa [KCTC 1637], S. epidermidis [KCTC 1917] and S. aureus [KCTC1621]
Concentration: 0-256 μg/mL
Incubation Time: 18-24 h
Result: Inhibited bacterial growth with MICs of 8, 4, 4 and 4 μg/mL against E. coli [KCTC 1682], P. aeruginosa [KCTC 1637], S. epidermidis [KCTC 1917] and S. aureus [KCTC1621], respectively.

RT-PCR[1]

Cell Line: LPS-stimulated RAW 264.7 macrophages
Concentration: 5 μg/mL (for NO/iNOS) and 20 μg/mL (for TNF-α)
Incubation Time: 18 h
Result: Effectively inhibited the production and expression of NO and TNF-α from LPS-stimulated RAW 264.7 cells.
分子量

769.04

Formula

C40H64N16
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antimicrobial agent-6 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antimicrobial agent-62978694-10-7Antimicrobial agent6Antimicrobial agent 6Bacterialantimicrobialanti-inflammatoryE. coliP. aeruginosaS. epidermidisS. aureusInhibitorinhibitorinhibit

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