2. Cell Cycle/DNA Damage PI3K/Akt/mTOR
  3. ATM/ATR
  4. ATM-IN-1

ATM-IN-1 是一种有效的 ATM 抑制剂。ATM 主要位于细胞核和微粒体中，参与细胞周期进程和细胞周期检查点对 DNA 损伤的反应。ATM-IN-1 具有研究癌症和神经疾病的潜力 (摘自专利 WO2021139814A1，化合物 3)。

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ATM-IN-1 Chemical Structure

ATM-IN-1 Chemical Structure

CAS No. : 2662761-76-2

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ATM-IN-1 相关抗体

Top Publications Citing Use of Products

查看 ATM/ATR 亚型特异性产品:

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ATM ATR

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ATM-IN-1 is a potent inhibitor of ATM. ATM is located mainly in the nucleus and microsomes and is involved in cell cycle progression and in the cell cycle checkpoint response to DNA damage. ATM-IN-1 has the potential for the research of cancer and neurology diseases (extracted from patent WO2021139814A1, compound 3)[1].

分子量

528.65

Formula

C30H36N6O3
CAS 号
非同位 CAS

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ATM-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATM-IN-12662761-76-2ATM/ATRAtaxia telangiectasia mutatedATM and RAD3 relatedATMnucleusmicrosomescell cycle progressionDNA damagecancerneurologyInhibitorinhibitorinhibit

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