2. Metabolic Enzyme/Protease
  3. HMG-CoA Reductase (HMGCR)
  4. Bemfivastatin hemicalcium

Bemfivastatin hemicalcium  (Synonyms: PPD 10558 hemicalcium)

目录号: HY-106281A 纯度: 98.00%
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摩尔计算器

Bemfivastatin (PPD 10558) hemicalcium 是一种口服有效的降脂剂和 HMG-CoA 还原酶抑制剂。Bemfivastatin hemicalcium 可增强肝脏提取的活性。未观察到的不良反应水平 (NOAEL) 的给药剂量分别为 ≥320 mg/kg/d (大鼠发育毒性)，≥12.5 mg/kg/d (家兔母毒性)，≥25 mg/kg/d (家兔发育毒性)。Bemfivastatin hemicalcium 可用于他汀类药物不能耐受的他汀相关性高胆固醇血症性肌痛的研究。

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Bemfivastatin hemicalcium Chemical Structure

Bemfivastatin hemicalcium Chemical Structure

CAS No. : 805241-64-9

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规格 价格 是否有货 数量
5 mg ￥1500
In-stock
10 mg ￥2400
In-stock
25 mg ￥4850
In-stock
50 mg ￥7800
In-stock
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200 mg   询价  

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Other Forms of Bemfivastatin hemicalcium:

Bemfivastatin hemicalcium 相关抗体

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  • 生物活性

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生物活性

Bemfivastatin (PPD 10558) hemicalcium is an orally active lipid-lowering agent and HMG-CoA reductase inhibitor. Bemfivastatin hemicalcium enhances the activity of liver extracts. Bemfivastatin hemicalcium has no-observed adverse effect levels (NOAEL) with dosages of ≥320 mg/kg/d (rat developmental toxicity), ≥12.5 mg/kg/d (rabbit maternal toxicity), ≥25 mg/kg/d (rabbit developmental toxicity), respectively. Bemfivastatin hemicalcium can be used in the study of statin-related hypercholesterolemic myalgia in statin-intolerant patients.

分子量

607.74

Formula

C34H37FN2O6.1/2Ca
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

Bemfivastatin hemicalcium 相关分类

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Keywords:

Bemfivastatin hemicalcium805241-64-9PPD 10558 hemicalciumHMG-CoA Reductase (HMGCR)Inhibitorinhibitorinhibit

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