2. GPCR/G Protein Neuronal Signaling
  3. Cannabinoid Receptor
  4. CB2R probe 1

CB2R probe 1 是一种安全绿色的 CB2R (2 型大麻素受体) 荧光探针，Ki 为 130 nM。CB2R probe 1 在癌细胞中显示出低细胞毒性。

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CB2R probe 1 Chemical Structure

CB2R probe 1 Chemical Structure

CAS No. : 2634714-79-5

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CB2R probe 1 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CB2R probe 1 is a safe and green CB2R (cannabinoid 2 receptor) fluorescent probe with an Ki of 130 nM. CB2R probe 1 shows low cytotoxicity in cancer cells[1].

IC50 & Target[1]

cannabinoid type-2 receptors

130 nM (Ki)

体外研究
(In Vitro)

CB2R probe 1 (compound 28) (100 nM; 24 h) shows low cytotoxicity with IC50s of 1.6, 1.4, 1.4, 1.1, 2.6, 0.55, 2.0, 2.4, 2.8 nM for PANC1, U2OS, HT29, HT29-DX, U87AD, PC3, CB2R-HEK293, MCF7, MCFT-DX cells, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CB2R probe 1 相关抗体:
分子量

594.74

Formula

C36H42N4O4
CAS 号
Unlabeled Cas

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CB2R probe 1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CB2R probe 12634714-79-5Cannabinoid Receptorfluorescent ligandsCB2R-HEK293 cellslow cytotoxicityMCF7MCFT-DX cellsInhibitorinhibitorinhibit

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