2. Immunology/Inflammation Anti-infection
  3. Enterovirus Interleukin Related
  4. Citrullinated LL-37 2cit

Citrullinated LL-37 2cit 是一种瓜氨酸化 LL-37 (HY-P1222) 肽。Citrullinated LL-37 2cit 在 10 μg/mL 时降低 LL-37 对 HRV 的活性，降低 LL-37 的抑菌作用。Citrullinated LL-37 2cit 引起 RV1B 诱导的 IL-8、CCL5 和 IL-6 mRNA 水平的降低。Citrullinated LL-37 2cit 显示降低 HRV 诱导的 CCL5 分泌的能力中度下降。

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Custom Peptide Synthesis

Citrullinated LL-37 2cit Chemical Structure

Citrullinated LL-37 2cit Chemical Structure

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Citrullinated LL-37 2cit 相关抗体

Top Publications Citing Use of Products

  • 生物活性

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生物活性

Citrullinated LL-37 2cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 2cit reduces LL-37 activity against HRV at 10 μg/mL and reduces the antibacterial effect of LL-37. Citrullinated LL-37 2cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B. Citrullinated LL-37 2cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion[1].

IC50 & Target

Human rhinovirus[1]
分子量

4495.23

Formula

C205H338N58O55
Sequence

Leu-Leu-Gly-Asp-Phe-Phe-{Cit}-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-{Cit}-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser
Sequence Shortening

LLGDFF-{Cit}-KSKEKIGKEFK-{Cit}-IVQRIKDFLRNLVPRTES
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Citrullinated LL-37 2cit 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Citrullinated LL-37 2citEnterovirusInterleukin RelatedRhinovirusHRVHRVsHEVHEVsILhuman rhinovirusWI-38IL-8CCL5IL-6S. aureusInhibitorinhibitorinhibit

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