1. Immunology/Inflammation Apoptosis
  2. COX Apoptosis
  3. COX-2-IN-43

COX-2-IN-43 (Compound MYM4) 是一种 COX-2 抑制剂 (IC50: 对 COX-1COX-2 分别为 0.983 和 0.247 μM)。COX-2-IN-43 抑制癌细胞增殖和定植,诱导细胞凋亡 (Apoptosis)。

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COX-2-IN-43 Chemical Structure

COX-2-IN-43 Chemical Structure

CAS No. : 1023524-40-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

COX-2-IN-43 (Compound MYM4) is a COX-2 inhibitor (IC50: 0.983 and 0.247 μM for COX-1 and COX-2 respectively). COX-2-IN-43 inhibits cancer cell proliferation and colonization, induces apoptosis[1].

IC50 & Target[1]

COX-1

0.983 μM (IC50)

COX-2

0.247 μM (IC50)

体外研究
(In Vitro)

COX-2-IN-43 抑制 CaCo-2, Hep3B, and HeLa 癌细胞的增殖, IC50 分别为 10.22, 4.84, and 1.57 μM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

431.19

Formula

C18H11Cl2F3N2O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

COX-2-IN-43 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
COX-2-IN-43
目录号:
HY-163509
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