1. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease Apoptosis
  2. Reactive Oxygen Species Apoptosis
  3. Dithiodipropionic acid

Dithiodipropionic acid  (Synonyms: 3,3'-二硫代二丙酸)

目录号: HY-W014395 纯度: ≥99.0%
COA 产品使用指南

Dithiodipropionic acid 可与 CPUL1 (HY-151802, TrxR 抑制剂) 相互作用 形成纳米聚集体 (CPUL1-DA NAs)。CPUL1-DA NAs 可比游离 CPUL1 产生更丰富的活性氧 (ROS) 并诱导细胞凋亡 (apoptosis),提高抗 HUH7 癌细胞的抗肿瘤功效。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Dithiodipropionic acid Chemical Structure

Dithiodipropionic acid Chemical Structure

CAS No. : 1119-62-6

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
5 g ¥200
In-stock
10 g   询价  
50 g   询价  

* Please select Quantity before adding items.

Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dithiodipropionic acid can interact with CPUL1 (HY-151802, a TrxR inhibitor) to form nanoaggregates (CPUL1-DA NAs). CPUL1-DA NAs generates more abundant ROS to induce cell apoptosis than that of free CPUL1, and improves antitumor efficacy against HUH7 cancer cells[1].

体外研究
(In Vitro)

CPUL1-DA NAs (molar ratio was 1:2) inhibits HUH7 hepatoma cell viability with an IC50 value of 4.3 μM, and has weak cytotoxicity against normal L02 cells[1].
CPUL1-DA NAs (2.5-10 μM, 6 h) can be more effectively enriched in HUH7 cells mitochondria and displays faster cellular uptake ability to deliver CPUL1 into cells than that of free CPUL1[1].
CPUL1-DA NAs (2.5-10 μM, 12 h) results in the accumulation of superoxides and mitochondrial membrane damage in HUH7 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

210.26

Formula

C6H10O4S2

CAS 号
性状

固体

颜色

White to off-white

中文名称

3,3'-二硫代二丙酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥99.0%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Dithiodipropionic acid
目录号:
HY-W014395
需求量: