2. Metabolic Enzyme/Protease
  3. Dipeptidyl Peptidase
  4. DPP-8/9 probe-1

DPP-8/9 probe-1 (compound 20) 是靶向二肽基肽酶 (Dipeptidyl Peptidase) DPP8/9 的荧光探针，能够通过荧光显微镜在体外选择性标记和可视化活性 DPP8/9。DPP-8/9 probe-1 含有硝基苯并恶二唑 (NBD) 标记，对 DPP8/9 比相关 S9 家族成员具有高亲和力和选择性 (IC50 分别为 210 nM 和 15 nM)。

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DPP-8/9 probe-1 Chemical Structure

DPP-8/9 probe-1 Chemical Structure

CAS No. : 3020859-80-4

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DPP-8/9 probe-1 相关抗体

Top Publications Citing Use of Products

查看 Dipeptidyl Peptidase 亚型特异性产品:

查看所有亚型
DPP-1 DPP-2 DPP-4 DPP-8 DPP-9

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively).[9][1].

IC50 & Target

DPP-8

210 nM (IC50, [1])

DPP-9

15 nM (IC50, [1])

DPP-4

.44 μM (IC50, [1])

体外研究
(In Vitro)

DPP-8/9 probe-1 (compound 20) (10 μM; 30 min) 可显著染色并可视化 THP 细胞中的 DPP-8/9[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

DPP-8/9 probe-1 相关抗体:

Immunofluorescence[1]

Cell Line: THP-1 monocytes
Concentration: 0.5 μM, 1 μM, 2 μM, 10 μM
Incubation Time: 30 min
Result: Lower concentrations (0.5 μM, 1 μM and 2 μM) can not be sufficient for in-cell staining
Sta
分子量

637.66

Formula

C31H36FN7O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DPP-8/9 probe-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DPP-8/9 probe-13020859-80-4Dipeptidyl PeptidaseDPPBiotinChemical toolsDipeptidyl peptidase 8Dipeptidyl peptidase 9FluorescenceProbeInhibitorinhibitorinhibit

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目录号：
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