2. Immunology/Inflammation
  3. CD22
  4. Epratuzumab

Epratuzumab  (Synonyms: Antibody hLL 2; Anti-Human CD22 Recombinant Antibody)

目录号: HY-P99289 纯度: ≥95.0%
COA

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Epratuzumab (Antibody hLL 2) 是一种抗 CD22 IgG1 单克隆抗体。Epratuzumab 也是一种肿瘤显像剂和免疫调节剂。Epratuzumab 可诱导 CD22 磷酸化。Epratuzumab 已被用于研究非霍奇金淋巴瘤和一些自身免疫性疾病。

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Epratuzumab Chemical Structure

Epratuzumab Chemical Structure

CAS No. : 205923-57-5

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规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥7800
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Epratuzumab 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Epratuzumab (Antibody hLL 2) is an anti-CD22 IgG1 monoclonal antibody. Epratuzumab is also a tumor-imaging agent and an immunomodulatory agent. Epratuzumab can induce CD22 phosphorylation. Epratuzumab has been used to research non-Hodgkin’s lymphomas (NHL) and certain autoimmune diseases[1].

同型

Human IgG4 kappa
推荐同型对照抗体
种属

Humanized
体外研究
(In Vitro)

Epratuzumab binds to CD22 ECD on Biacore with a KD of 0.7 nM, and resulting CD22 phosphorylation[1]. Epratuzumab (0-100 μM; 1h) results in a dose dependent increase in CD22 internalization in Daudi lymphoma cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Epratuzumab 相关抗体:
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥95.0%

COA (150 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Epratuzumab 相关分类

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Keywords:

Epratuzumab205923-57-5Antibody hLL 2 Anti-Human CD22 Recombinant AntibodyAntibody hLL2Antibody hLL-2CD22Siglec 2non-Hodgkin’s lymphomasanticancerInhibitorinhibitorinhibit

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