2. Gene
  3. CD96 - CD96 molecule Gene

CD96 - CD96 molecule Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：CD96 分子

种属: Homo sapiens

同用名: TACTILE

基因 ID: 10225 | 基因类型: protein coding

关于 CD96

Cytogenetic location: 3q13.13-q13.2 Genomic coordinates (GRCh38): 3:111,542,197-111,665,996 (from NCBI)

This gene has 7 transcripts (splice variants), 106 orthologues and is associated with 3 phenotypes. Broad expression in lymph node (RPKM 4.8), appendix (RPKM 2.7) and 15 other tissues.

功能概要

该基因编码的蛋白质属于免疫球蛋白超家族。它是一种 I 型膜蛋白。在免疫反应的后期，该蛋白质可能在活化的 T 细胞和 NK 细胞的粘附相互作用中发挥作用。它也可能在抗原呈递中起作用。选择性剪接会生成编码不同异构体的多个转录变体。[RefSeq 提供，2016 年 1 月]

The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]

CD96 基因产物(4)

mRNA Protein Name
NM_001318889.2 NP_001305818.1 T-cell surface protein tactile isoform 3
NM_001410800.1 NP_001397729.1 T-cell surface protein tactile isoform 4
NM_005816.5 NP_005807.1 T-cell surface protein tactile isoform 2 precursor
NM_198196.3 NP_937839.1 T-cell surface protein tactile isoform 1 precursor

CD96 蛋白结构

Ig_2

Ig_2: Immunoglobulin domain (25 - 135)

Ig_3

Ig_3: Immunoglobulin domain (271 - 357)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 585 a.a.
蛋白主名 其他名称

T-cell surface protein tactile

T cell activation, increased late expression

重组 CD96 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72698 CD96 Protein, Human (HEK293, His) P40200-2 (V22-M503) ≥95%
HY-P75371 CD96 Protein, Human (Biotinylated, HEK293, His) P40200-2 (V22-M503) ≥95%
HY-P75372 CD96 Protein, Human (503a.a, HEK293, His) P40200-2 (M1-M503) ≥95%
HY-P78420 CD96 Protein, Human (HEK293, mFc) P40200-2 (V22-M503) ≥95%
HY-P78660 CD96 Protein, Human (C110S, HEK293, His) P40200-2 (V22-M503, C110S) ≥95%
HY-P700855 CD96 Protein, Human (Biotinylated, HEK293, His-Avi) P40200-2 (V22-M503) ≥95%

关联疾病

疾病名称 别名
C Syndrome

Opitz Trigonocephaly Syndrome

Trigonocephaly

Trigonocephaly Syndrome

Trigonocephaly C Syndrome

Opitz C Trigonocephaly

Opitz Trigonocephaly C Syndrome

Otcs

CSYN
Leukemia, Acute Myeloid

Acute Myeloid Leukemia

Leukemia, Acute Myelogenous

Acute Myelogenous Leukemia

AML

Leukemia, Acute Myeloid, Susceptibility To

Acute Myeloblastic Leukemia

Leukemia, Acute Myeloid, Reduced Survival In, Somatic

Acute Myeloid Leukaemia

Leukemia, Myelocytic, Acute

Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

Secondary Aml

Acute Myelocytic Leukemia

Acute Myeloid Leukemia, Somatic

Leukemia, Acute Myeloid, Somatic

Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

Acute Myeloblastic Leukaemia

Acute Myelogenous Leukaemia

Aml - Acute Myeloid Leukemia

Acute Myeloid Leukemia With Cebpa Somatic Mutations

Aml With Cebpa Somatic Mutations

Inherited Acute Myeloid Leukemia

Familial Aml

Inherited Aml

Pure Familial Aml

Pure Familial Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Therapy-Related Aml And Myelodysplastic Syndrome

Acute Myeloid Leukemia, Secondary

Acute Non-Lymphoblastic Leukemia

Acute Non-Lymphocytic Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Myeloblastic Leukaemia With Multilineage Dysplasia

Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

Acute Myeloid Leukaemia With Myelodysplasia-Related Features
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02279 CD96 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus CD96 VGNC VGNC:102640
Bos taurus CD96 VGNC VGNC:27054
Canis familiaris CD96 VGNC VGNC:38982
Rattus norvegicus CD96 RGD RGD:1565249
Macaca mulatta CD96 VGNC VGNC:70773
Mus musculus CD96 MGD MGI:1934368
Macaca fascicularis CD96 NCBI
Others CD96 NCBI
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