1. Gene
  2. Bcl2l10 - Bcl2-like 10 Gene

Bcl2l10 - Bcl2-like 10 Gene

中文名称:Bcl2 样10

种属: Rattus norvegicus

基因 ID: 114552 | 基因类型: protein coding

关于 Bcl2l10

Primary_assembly 8: 76,107,326-76,113,367 forward strand.mRatBN7.2:CM026981.1

This gene has 1 transcript (splice variant), 132 orthologues, 13 paralogues and is associated with 7 phenotypes. Biased expression in Brain (RPKM 8.8), Adrenal (RPKM 4.9) and 7 other tissues.

功能概要

预测该基因编码的蛋白可启动半胱天冬酶结合活性;蛋白质异二聚化活性;和蛋白质同二聚化活性。参与少突胶质细胞分化。预计位于几种细胞成分中,包括细胞质;线粒体相关内质网膜;和线粒体。预计在线粒体外膜中有活性。该基因的人类直系同源物与多发性骨髓瘤有关;骨髓增生异常综合症;和胃癌。与人类 BCL2L10 同源(BCL2 like 10)。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable Caspase binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in oligodendrocyte differentiation. Predicted to be located in several cellular components, including cytosol; mitochondria-associated endoplasmic reticulum membrane; and mitochondrion. Predicted to be active in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10). [provided by Alliance of Genome Resources, Apr 2022]

Bcl2l10 基因产物(1)

mRNA Protein Name
NM_053733.1 NP_446185.1 bcl-2-like protein 10

Bcl2l10 蛋白结构

Bcl-2_like

Bcl-2_like: cd06845 (5 - 150)

  • 0
  • 100
  • 185 a.a.
蛋白主名 其他名称

bcl-2-like protein 10

BCL2-like 10 (apoptosis facilitator)

anti-apoptotic protein Boo

apoptosis regulator Bcl-B

bcl2-L-10

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bcl2l10 NCBI NCBI:10017