Acvr2a - activin receptor IIA Gene

中文名称：激活素受体 IIA

种属: Mus musculus

同用名: Acvr2; ActrIIa; TactrII

关于 Acvr2a

功能概要

该基因编码的蛋白可启动多种功能，包括 BMP 受体活性； PDZ 域绑定活动；和激活素结合活性。作用于多个过程的上游或内部，包括支持细胞增殖；交配;和胚胎骨骼系统发育。位于细胞表面。以多种结构表达，包括中枢神经系统；早孕;性腺;直觉;和感觉器官。用于研究 Weissenbacher-Zweymuller 综合征。该基因的人类直系同源物与结肠癌有关。与人类 ACVR2A（2A 型激活素 A 受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including BMP Receptor activity; PDZ domain binding activity; and activin binding activity. Acts upstream of or within several processes, including Sertoli cell proliferation; copulation; and embryonic skeletal system development. Located in cell surface. Is expressed in several structures, including central nervous system; early conceptus; gonad; gut; and sensory organ. Used to study Weissenbacher-Zweymuller syndrome. Human ortholog(s) of this gene implicated in colon Cancer. Orthologous to human ACVR2A (Activin A receptor type 2A). [provided by Alliance of Genome Resources, Apr 2022]