1. Gene
  2. Bcl2l10 - Bcl2-like 10 Gene

Bcl2l10 - Bcl2-like 10 Gene

中文名称:Bcl2 样10

种属: Mus musculus

同用名: Boo; Diva

基因 ID: 12049 | 基因类型: protein coding

关于 Bcl2l10

Chromosome 9: 75,255,040-75,258,931 forward strand.GRCm39:CM001002.3

This gene has 1 transcript (splice variant), 23 orthologues and is associated with 1 phenotype. Biased expression in ovary adult (RPKM 8.8) and subcutaneous fat pad adult (RPKM .4).

功能概要

实现相同的蛋白质结合活性。在没有配体的情况下,作用于外在凋亡信号通路的负调节上游或负调节内;内在凋亡信号通路的负调节;和细胞凋亡过程的正调控。位于膜内。在孕早期表达;附睾;脑膜;和卵巢。该基因的人类直系同源物与多发性骨髓瘤有关;骨髓增生异常综合症;和胃癌。与人类 BCL2L10 同源(BCL2 like 10)。 [由基因组资源联盟提供,2022 年 4 月]

Enables identical protein binding activity. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of intrinsic apoptotic signaling pathway; and positive regulation of apoptotic process. Located in membrane. Is expressed in early conceptus; epididymis; meninges; and ovary. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10). [provided by Alliance of Genome Resources, Apr 2022]

Bcl2l10 基因产物(1)

mRNA Protein Name
NM_013479.2 NP_038507.1 bcl-2-like protein 10

Bcl2l10 蛋白结构

BCL

BCL: smart00337 (41 - 150)

  • 0
  • 100
  • 191 a.a.
蛋白主名 其他名称

bcl-2-like protein 10

anti-apoptotic protein Boo

apoptosis regulator Bcl-B

bcl-2 homolog Diva

bcl2-L-10

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bcl2l10 NCBI NCBI:10017