2. Gene
  3. Ccr6 - chemokine (C-C motif) receptor 6 Gene

Ccr6 - chemokine (C-C motif) receptor 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：趋化因子 (CC 基序) 受体 6

种属: Mus musculus

同用名: CCR-6; KY411; Cmkbr6; CC-CKR-6

基因 ID: 12458 | 基因类型: protein coding

关于 Ccr6

Chromosome 17: 8,454,875-8,475,973 forward strand.GRCm39:CM001010.3

This gene has 9 transcripts (splice variants), 299 orthologues, 25 paralogues and is associated with 58 phenotypes. Biased expression in spleen adult (RPKM 9.8), mammary gland adult (RPKM 4.1) and 5 other tissues.

功能概要

该基因编码的蛋白可启动 CC 趋化因子结合活性和 CC 趋化因子受体活性。参与多个过程，包括免疫系统发育；白细胞迁移；和细胞运动的调节。位于质膜外侧；精子质膜；和精子的主要部分。以多种结构表达，包括中枢神经系统；直觉;免疫系统;雄性生殖腺或器官；和视网膜。与人 CCR6（CC 基序趋化因子受体 6）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables C-C chemokine binding activity and C-C Chemokine Receptor activity. Involved in several processes, including immune system development; leukocyte migration; and regulation of cell motility. Located in external side of plasma membrane; sperm plasma membrane; and sperm principal piece. Is expressed in several structures, including central nervous system; gut; immune system; male reproductive gland or organ; and retina. Orthologous to human CCR6 (C-C motif Chemokine Receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Ccr6 基因产物(7)

mRNA Protein Name
NM_001190335.1 NP_001177264.1 C-C chemokine receptor type 6 isoform A
NM_001190334.1 NP_001177263.1 C-C chemokine receptor type 6 isoform A
NM_001190336.1 NP_001177265.1 C-C chemokine receptor type 6 isoform A
NM_001190333.1 NP_001177262.1 C-C chemokine receptor type 6 isoform A
NM_009835.4 NP_033965.1 C-C chemokine receptor type 6 isoform A
NM_001190338.1 NP_001177267.1 C-C chemokine receptor type 6 isoform B
NM_001190337.1 NP_001177266.1 C-C chemokine receptor type 6 isoform A

Ccr6 蛋白结构

7tmA_CCR6

7tmA_CCR6: cd15172 (38 - 65)

7tmA_CCR6

7tmA_CCR6: cd15172 (38 - 318)

7tmA_CCR6

7tmA_CCR6: cd15172 (72 - 97)

7tmA_CCR6

7tmA_CCR6: cd15172 (109 - 139)

7tmA_CCR6

7tmA_CCR6: cd15172 (153 - 175)

7tmA_CCR6

7tmA_CCR6: cd15172 (202 - 231)

7tmA_CCR6

7tmA_CCR6: cd15172 (238 - 268)

7tmA_CCR6

7tmA_CCR6: cd15172 (286 - 311)

  • 0
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  • 300
  • 367 a.a.
蛋白主名 其他名称

C-C chemokine receptor type 6

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-148531 PF-07054894 Inhibitor 99.12% Phase 1
Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-151435 CCR6 antagonist 1 Antagonist 99.55% 否
HY-112701 CCR6 inhibitor 1 Inhibitor 99.60% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccr6 NCBI NCBI:1235
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