2. Gene
  3. Ccr8 - chemokine (C-C motif) receptor 8 Gene

Ccr8 - chemokine (C-C motif) receptor 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：趋化因子 (CC 基序) 受体 8

种属: Mus musculus

同用名: C-C; CCR-8; CKR-8; mCCR8; Cmkbr8; CC-CKR-8; C-C CKR-8

基因 ID: 12776 | 基因类型: protein coding

关于 Ccr8

Chromosome 9: 119,921,180-119,923,972 forward strand.GRCm39:CM001002.3

This gene has 1 transcript (splice variant), 236 orthologues, 25 paralogues and is associated with 7 phenotypes. Biased expression in thymus adult (RPKM 6.3), mammary gland adult (RPKM 1.1) and 3 other tissues.

功能概要

该基因编码的蛋白可启动 CC 趋化因子受体活性。在趋化性上游或趋化性内起作用。预测位于质膜中。预计是膜的组成部分。预计在质膜外侧活跃。在中枢神经系统中表达；视网膜；和胸腺原基。与人 CCR8（CC 基序趋化因子受体 8）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables C-C Chemokine Receptor activity. Acts upstream of or within chemotaxis. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system; retina; and thymus primordium. Orthologous to human CCR8 (C-C motif Chemokine Receptor 8). [provided by Alliance of Genome Resources, Apr 2022]

Ccr8 基因产物(1)

mRNA Protein Name
NM_007720.2 NP_031746.1 C-C chemokine receptor type 8

Ccr8 蛋白结构

7tmA_CCR8

7tmA_CCR8: cd15187 (33 - 308)

7tmA_CCR8

7tmA_CCR8: cd15187 (33 - 60)

7tmA_CCR8

7tmA_CCR8: cd15187 (67 - 92)

7tmA_CCR8

7tmA_CCR8: cd15187 (103 - 133)

7tmA_CCR8

7tmA_CCR8: cd15187 (145 - 167)

7tmA_CCR8

7tmA_CCR8: cd15187 (192 - 221)

7tmA_CCR8

7tmA_CCR8: cd15187 (228 - 258)

7tmA_CCR8

7tmA_CCR8: cd15187 (276 - 301)

  • 0
  • 100
  • 200
  • 300
  • 353 a.a.
蛋白主名 其他名称

C-C chemokine receptor type 8

C-C motif chemokine receptor 8

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101038A ZK756326 dihydrochloride Agonist 99.88% 否
HY-122219 R243 Antagonist 98.01% 否
HY-119217 AZ084 Antagonist 99.69% 否
HY-124416 ML604086 Inhibitor 99.80% 否
HY-121885 LMD-009 Agonist 99.76% 否
HY-144197 CCR8 antagonist 1 Antagonist 98.71% 否
HY-144200 CCR8 antagonist 2 Antagonist 99.71% 否
HY-153669 SB-649701 Antagonist / 否
HY-160647 CCR8 antagonist 3 Antagonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccr8 NCBI NCBI:1237
Macaca fascicularis Ccr8 NCBI NCBI:102132857
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