Il10 - interleukin 10 Gene

中文名称：白细胞介素 10

种属: Rattus norvegicus

同用名: If2a; IL10X

关于 Il10

功能概要

该基因编码的蛋白可启动白细胞介素 10 受体结合活性。参与多个过程，包括细胞对雌二醇刺激的反应；肝再生；一氧化氮生物合成过程的负调控。位于细胞外空间。用于研究多种疾病，包括肺部疾病（多种）；围产期坏死性小肠结肠炎；坐骨神经病;中毒性脑病;和短暂性脑缺血。多种疾病的生物标志物，包括动脉疾病（多种）；褥疮;肺部疾病（多发）；阻塞性睡眠呼吸暂停;和产后抑郁症。该基因的人类直系同源物与多种疾病有关，包括动脉疾病（多种）；自身免疫性疾病（多种）；眼病（多发）；胃肠系统癌症（多发性）；和血液系统癌症（多种）。与人 IL10（白细胞介素 10）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables interleukin-10 receptor binding activity. Involved in several processes, including cellular response to estradiol stimulus; liver regeneration; and negative regulation of nitric oxide biosynthetic process. Located in extracellular space. Used to study several diseases, including lung disease (multiple); perinatal necrotizing enterocolitis; sciatic neuropathy; toxic encephalopathy; and transient cerebral ischemia. Biomarker of several diseases, including artery disease (multiple); decubitus ulcer; lung disease (multiple); obstructive sleep apnea; and postpartum depression. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); gastrointestinal system Cancer (multiple); and hematologic Cancer (multiple). Orthologous to human IL10 (interleukin 10). [provided by Alliance of Genome Resources, Apr 2022]