1. Gene
  2. Map2k5 - mitogen activated protein kinase kinase 5 Gene

Map2k5 - mitogen activated protein kinase kinase 5 Gene

中文名称:有丝分裂原活化蛋白激酶激酶 5

种属: Rattus norvegicus

同用名: Mek5

基因 ID: 29568 | 基因类型: protein coding

关于 Map2k5

Primary_assembly 8: 63,625,221-63,851,983 reverse strand.mRatBN7.2:CM026981.1

This gene has 4 transcripts (splice variants), 209 orthologues, 8 paralogues and is associated with 9 phenotypes.

功能概要

该基因编码的蛋白可启动 ATP 结合活性和蛋白激酶活性。涉及多个进程,包括ERK5级联;细胞凋亡过程的负调控;和基因表达的调控。位于细胞质和细胞核中。与人 MAP2K5(丝裂原活化蛋白激酶激酶 5)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables ATP binding activity and protein kinase activity. Involved in several processes, including ERK5 cascade; negative regulation of apoptotic process; and regulation of gene expression. Located in cytosol and nucleus. Orthologous to human MAP2K5 (mitogen-activated protein kinase kinase 5). [provided by Alliance of Genome Resources, Apr 2022]

Map2k5 基因产物(2)

mRNA Protein Name
NM_001033987.1 NP_001029159.1 dual specificity mitogen-activated protein kinase kinase 5 isoform a
NM_017246.2 NP_058942.1 dual specificity mitogen-activated protein kinase kinase 5 isoform b

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map2k5 NCBI NCBI:5607