2. Gene
  3. Map2k2 - mitogen activated protein kinase kinase 2 Gene

Map2k2 - mitogen activated protein kinase kinase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：有丝分裂原活化蛋白激酶激酶 2

种属: Rattus norvegicus

同用名: Prkmk2

基因 ID: 58960 | 基因类型: protein coding

关于 Map2k2

Primary_assembly 7: 8,580,905-8,610,243 reverse strand.mRatBN7.2:CM026980.1

This gene has 5 transcripts (splice variants), 273 orthologues, 8 paralogues and is associated with 25 phenotypes. Biased expression in Kidney (RPKM 39.2), Muscle (RPKM 261.5) and 9 other tissues.

功能概要

该基因编码的蛋白可启动 ATP 结合活性和 MAP 激酶激酶活性。参与基因表达和蛋白质磷酸化的负调控。位于细胞皮质和细胞质中。该基因的人类直系同源物与心面皮肤综合征 4 和小肠腺癌有关。与人 MAP2K2（丝裂原活化蛋白激酶激酶 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables ATP binding activity and MAP kinase kinase activity. Involved in negative regulation of gene expression and protein phosphorylation. Located in cell cortex and cytosol. Human ortholog(s) of this gene implicated in cardiofaciocutaneous syndrome 4 and small intestine adenocarcinoma. Orthologous to human MAP2K2 (mitogen-activated protein kinase kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Map2k2 基因产物(1)

mRNA Protein Name
NM_133283.2 NP_579817.1 dual specificity mitogen-activated protein kinase kinase 2

Map2k2 蛋白结构

PKc_MEK

PKc_MEK: cd06615 (69 - 387)

  • 0
  • 100
  • 200
  • 300
  • 401 a.a.
蛋白主名 其他名称

dual specificity mitogen-activated protein kinase kinase 2

ERK activator kinase 2

MAP kinase kinase 2

MAPK/ERK kinase 2

MAPKK 2

MEK 2

MEK2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08036 MAP2K2 Human Pre-designed siRNA Set A / 否
HY-RS08037 Map2k2 Mouse Pre-designed siRNA Set A / 否
HY-RS08038 Map2k2 Rat Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map2k2 NCBI NCBI:5605
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