1. Gene
  2. AIMP2 - aminoacyl tRNA synthetase complex interacting multifunctional protein 2 Gene

AIMP2 - aminoacyl tRNA synthetase complex interacting multifunctional protein 2 Gene

中文名称:氨酰 tRNA 合成酶复合物相互作用多功能蛋白 2

种属: Homo sapiens

同用名: P38; JTV1; HLD17; JTV-1

基因 ID: 7965 | 基因类型: protein coding

关于 AIMP2

Cytogenetic location: 7p22.1 Genomic coordinates (GRCh38): 7:6,009,272-6,023,834 (from NCBI)

This gene has 4 transcripts (splice variants), 219 orthologues and is associated with 1 phenotype. Ubiquitous expression in testis (RPKM 18.6), duodenum (RPKM 17.0) and 25 other tissues.

功能概要

该基因编码的蛋白质是氨酰-tRNA 合成酶复合体的一部分,该复合体包含九种不同的氨酰-tRNA 合成酶和三种非酶促因子。编码的蛋白质是非酶因子之一,是复合物组装和稳定所必需的。[RefSeq 提供,2016 年 5 月]

The protein encoded by this gene is part of the Aminoacyl-tRNA Synthetase complex, which contains nine different aminoacyl-tRNA synthetases and three non-enzymatic factors. The encoded protein is one of the non-enzymatic factors and is required for assembly and stability of the complex. [provided by RefSeq, May 2016]

AIMP2 基因产物(8)

mRNA Protein Name
NM_001326606.2 NP_001313535.1 aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform b
NM_001326607.2 NP_001313536.1 aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform c
NM_001326609.2 NP_001313538.1 aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform d
NM_001326610.2 NP_001313539.1 aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform d
NM_001326611.3 NP_001313540.1 aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform d
NM_001362785.2 NP_001349714.1 aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform e
NM_001362787.2 NP_001349716.1 aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform f
NM_006303.4 NP_006294.2 aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform a

AIMP2 蛋白结构

GST_C_3

GST_C_3: Glutathione S-transferase, C-terminal domain (227 - 307)

  • 0
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  • 320 a.a.
蛋白主名 其他名称

aminoacyl tRNA synthase complex-interacting multifunctional protein 2

ARS-interacting multi-functional protein 2

重组 AIMP2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71538 AIMP2 Protein, Human (His) Q13155 (1M-320K) ≥95%

关联疾病

疾病名称 别名
Leukodystrophy, Hypomyelinating, 17

HLD17

Leukodystrophy, Hypomyelinating, 3

Hypomyelinating Leukodystrophy 3

HLD3

Pelizaeus-Merzbacher-Like Disease Due To Aimp1 Mutation

Leukodystrophy, Hypomyelinating 3

Perinatal Sudanophilic Leukodystrophy

Leukodystrophy, Hypomyelinating, Type 3

Pelizaeus-Merzbacher-Like Disease, Autosomal Recessive, 2

Leukodystrophy, Hypomyelinating, 7, With Or Without Oligodontia And/Or Hypogonadotropic Hypogonadism

HLD7

Leukoencephalopathy-Ataxia-Hypodontia-Hypomyelination Syndrome

Addh

Leukodystrophy, Hypomyelinating, With Hypodontia And Hypogonadotropic Hypogonadism

4h Syndrome

4h Leukodystrophy 1

Hypomyelinating Leukodystrophy 7 With Or Without Oligodontia And-Or Hypogonadotropic Hypogonadism

Hypomyelination-Cerebellar Atrophy-Hypoplasia Of The Corpus Callosum Syndrome

Leukodystrophy With Oligodontia

Tach Syndrome

Tremor-Ataxia-Central Hypomyelination Syndrome

Leukoencephalopathy, Hypomyelinating, With Ataxia And Delayed Dentition

Ataxia, Delayed Dentition, And Hypomyelination

Ataxia-Delayed Dentition-Hypomyelination Syndrome

Odontoleukodystrophy

Dentoleukoencephalopathy

Hypomyelinating Leukodystrophy-Ataxia-Hypodontia-Hypomyelination Syndrome

Ataxia-Delayed Dentition-Hypomyelination Syndrome

Ataxia Delayed Dentition And Hypomyelination

Leukodystrophy Hypomyelinating With Hypodontia And Hypogonadotropic Hypogonadism 4h Syndrome

Leukoencephalopathy Hypomyelinating With Ataxia And Delayed Dentition

Tach

Tremor-Ataxia With Central Hypomyelination

Attention Deficit Hyperactivity Disorder

Leukodystrophy, Dysmyelinating, With Oligodontia

Leukodystrophy

Leukodystrophies

Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly

Hypomyelinating Leukodystrophy

Hld

Leukodystrophy, Hypomyelinating

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta AIMP2 VGNC VGNC:69650
Bos taurus AIMP2 VGNC VGNC:25766
Mus musculus AIMP2 MGD MGI:2385237
Rattus norvegicus AIMP2 RGD RGD:1560787
Felis catus AIMP2 VGNC VGNC:80550
Others AIMP2 NCBI