2. Gene
  3. CDK5R2 - cyclin dependent kinase 5 regulatory subunit 2 Gene

CDK5R2 - cyclin dependent kinase 5 regulatory subunit 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：细胞周期蛋白依赖性激酶 5 调节亚基 2

种属: Homo sapiens

同用名: P39; NCK5AI; p39nck5ai

基因 ID: 8941 | 基因类型: protein coding

关于 CDK5R2

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:218,959,666-218,962,155 (from NCBI)

This gene has 1 transcript (splice variant), 190 orthologues and 1 paralogue.

功能概要

该基因编码的蛋白质是 CDK5 激酶的神经元特异性激活剂。它与 CDK5 结合形成活性激酶。这种蛋白质和神经元特异性 CDK5 激活剂 CDK5R1/p39NCK5A 都与细胞周期蛋白具有有限的相似性，因此可能定义了一个独特的细胞周期蛋白依赖性激酶激活蛋白家族。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008]

CDK5R2 基因产物(1)

mRNA Protein Name
NM_003936.5 NP_003927.1 cyclin-dependent kinase 5 activator 2

CDK5R2 蛋白结构

CDK5_activator

CDK5_activator: Cyclin-dependent kinase 5 activator protein (1 - 331)

  • 0
  • 100
  • 200
  • 300
  • 367 a.a.
蛋白主名 其他名称

cyclin-dependent kinase 5 activator 2

CDK5 activator 2

关联疾病

疾病名称 别名
Primary Microcephaly

True Microcephaly

Microcephaly, Primary
Lissencephaly

Pachygyria

Broad Gyri Of Cerebrum

Large Gyri Of Cerebrum

Macrogyria
Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02388 CDK5R2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus CDK5R2 VGNC VGNC:27129
Macaca mulatta CDK5R2 VGNC VGNC:70982
Rattus norvegicus CDK5R2 RGD RGD:1562530
Felis catus CDK5R2 VGNC VGNC:107505
Canis familiaris CDK5R2 VGNC VGNC:39056
Mus musculus CDK5R2 MGD MGI:1330828
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z