1. Gene
  2. MPZL1 - myelin protein zero like 1 Gene

MPZL1 - myelin protein zero like 1 Gene

中文名称:髓磷脂蛋白零样 1

种属: Homo sapiens

同用名: PZR; PZRa; PZRb; PZR1b; MPZL1b

基因 ID: 9019 | 基因类型: protein coding

关于 MPZL1

Cytogenetic location: 1q24.2 Genomic coordinates (GRCh38): 1:167,721,982-167,791,919 (from NCBI)

Ubiquitous expression in gall bladder (RPKM 26.1), placenta (RPKM 23.6) and 25 other tissues.

功能概要

预测可实现结构分子活性。预计参与细胞间信号传导和跨膜受体蛋白酪氨酸激酶信号通路。预计在细胞迁移的正调节上游或正调节内起作用。位于细胞表面和粘着斑。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable structural molecule activity. Predicted to be involved in cell-cell signaling and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within positive regulation of cell migration. Located in cell surface and focal adhesion. [provided by Alliance of Genome Resources, Apr 2022]

MPZL1 基因产物(3)

mRNA Protein Name
NM_001146191.2 NP_001139663.1 myelin protein zero-like protein 1 isoform c precursor
NM_003953.6 NP_003944.1 myelin protein zero-like protein 1 isoform a precursor
NM_024569.5 NP_078845.3 myelin protein zero-like protein 1 isoform b precursor

MPZL1 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (39 - 154)

  • 0
  • 100
  • 200
  • 269 a.a.
蛋白主名 其他名称

myelin protein zero-like protein 1

immunoglobulin family transmembrane protein

重组 MPZL1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70220 MPZL1 Protein, Human (HEK293, His) O95297 (S36-V162) ≥95%

关联疾病

疾病名称 别名
Noonan Syndrome With Multiple Lentigines

Leopard Syndrome

Multiple Lentigines Syndrome

Moynahan Syndrome

Cardiomyopathic Lentiginosis

Progressive Cardiomyopathic Lentiginosis

Cardio-Cutaneous Syndrome

Lentiginosis Profusa

Capute-Rimoin-Konigsmark-Esterly-Richardson Syndrome

Generalized Lentiginosis

Gorlin Syndrome Ii

Lentiginosis Profusa Syndrome

Lentigines, Electrocardiographic Conduction Abnormalities, Ocular Hypertelorism, Pulmonic Stenosis, Abnormal Genitalia, Retardation Of Growth, Deafnes

Diffuse Lentiginosis

Nsml

Familial Multiple Lentigines Syndrome

Alopecia-Epilepsy-Intellectual Disability Syndrome, Moynahan Type

Progressive Cardiomyopathic Lentiginosis Syndrome

Alopecia Epilepsy Oligophrenia Syndrome Of Moynahan

Charcot-Marie-Tooth Disease

Cmt

Hmsn

Hereditary Motor And Sensory Neuropathy

Pma

Cmt - Charcot-Marie-Tooth Disease

Charcot Marie Tooth Disease

Charcot-Marie-Tooth Hereditary Neuropathy

Charcot-Marie-Tooth Syndrome

Peroneal Muscular Atrophy

Hereditary Motor And Sensory Neuropathies

Rasopathy

Ras/Mitogen-Activated Protein Kinase Syndrome

Noonan Syndrome 1

Noonan Syndrome

NS1

Male Turner Syndrome

Female Pseudo-Turner Syndrome

Turner Phenotype With Normal Karyotype

Noonan Syndrome With Pigmented Villonodular Synovitis

Turner'S Phenotype, Karyotype Normal

Familial Turner Syndrome

Noonan'S Syndrome

Noonan-Ehmke Syndrome

Ns

Pseudo-Ullrich-Turner Syndrome

Turner Syndrome In Female With X Chromosome

Turner-Like Syndrome

Ullrich-Noonan Syndrome

Noonan-Like/Multiple Giant Cell Lesion Syndrome

Noonan Syndrome-Like Disorder With Multiple Giant Cell Lesions

Pterygium Colli Syndrome

Noonan Syndrome, Type 1

Turner Syndrome, Male

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus MPZL1 MGD MGI:1915731
Felis catus MPZL1 VGNC VGNC:68313
Rattus norvegicus MPZL1 RGD RGD:1359140
Macaca mulatta MPZL1 VGNC VGNC:100012
Bos taurus MPZL1 VGNC VGNC:31592
Canis familiaris MPZL1 VGNC VGNC:43354
Others MPZL1 NCBI