2. Anti-infection Others
  3. HIV Amino Acid Derivatives
  4. H-Gly-Pro-Gly-NH2

H-Gly-Pro-Gly-NH2 是一种抑制 HIV-1 复制的三肽。H-Gly-Pro-Gly-NH2 抑制 HIV-1 IIIB 和 HIV-2 ROD 的活性，EC50 值分别为 35 µM 和 30 µM。H-Gly-Pro-Gly-NH2 通过干扰衣壳形成来抑制 HIV-1 的体外复制。H-Gly-Pro-Gly-NH2 具有抗病毒活性，可用于病毒研究。

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Custom Peptide Synthesis

H-Gly-Pro-Gly-NH2 Chemical Structure

H-Gly-Pro-Gly-NH2 Chemical Structure

CAS No. : 141497-12-3

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H-Gly-Pro-Gly-NH2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

H-Gly-Pro-Gly-NH2 is a tripeptide that inhibits HIV-1 replication. H-Gly-Pro-Gly-NH2 inhibits the activity of HIV-1 IIIB and HIV-2 ROD with EC50 values of 35 µM and 30 µM, respectively. H-Gly Pro Gly NH2 inhibits HIV-1 replication in vitro by interfering with capsid formation. H-Gly Pro Gly NH2 has antiviral activity and can be used for virus research[1][2][3].

IC50 & Target[3]

HIV (IIIB)

35 μM (EC50)

HIV-2 (ROD)

30 μM (EC50)

体外研究
(In Vitro)

H-Gly-Pro-Gly-NH2 (5、20 和 100 µM) 在感染 HIV-1 SF-2 的 HUT78 细胞中显示抗病毒活性[1]。
H-Gly-Pro-Gly-NH2 (100 µM) 在 ACH-2 细胞中破坏 HIV-1 病毒粒子的衣壳[1]。
H-Gly-Pro-Gly-NH2 对临床 HIV-1 的抗病毒活性[2]

T215Y/F K70R M184V L74V T69D
Mean IC50 (µM) 16 17 20 12 17
K103N Y181C G48V L90M V82A/T M46I/L
Mean IC50 (µM) 13 21 16 18 16 17

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

H-Gly-Pro-Gly-NH2 相关抗体:
分子量

228.25

Formula

C9H16N4O3
CAS 号
Sequence

H-Gly-Pro-Gly-NH2
Sequence Shortening

GPG-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

H-Gly-Pro-Gly-NH2 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H-Gly-Pro-Gly-NH2141497-12-3HIVAmino Acid DerivativesHuman immunodeficiency virusGPG-NH2HUT78 cellsACH-2 cellsInhibitorinhibitorinhibit

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