1. Anti-infection
  2. HBV
  3. HEC72702

HEC72702 是一种有效的口服活性乙型肝炎病毒衣壳 (hepatitis B virus capsid) 抑制剂,EC50 值为 0.039 µM。HEC72702 剂量依赖性地减少血浆和肝脏中的 HBV DNA。

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HEC72702 Chemical Structure

HEC72702 Chemical Structure

CAS No. : 1793063-59-8

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HEC72702 is a potent and orally active hepatitis B virus capsid inhibitor with an EC50 values of 0.039 µM. HEC72702 dose-dependently reduced HBV DNA in both the plasma and livers[1].

IC50 & Target

EC50: 0.039 µM (hepatitis B virus capsid)[1]

体内研究
(In Vivo)

HEC72702 (50、100 mg/kg;口服;每日一次,连续 7 天) 剂量依赖性地减少血浆和肝脏中的 HBV DNA 拷贝数[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-7 weeks, 16-18 g, Female BALB/c mice(HDI mouse model)[1]
Dosage: 50, 100 mg/kg
Administration: P.o.; daily for 7 days
Result: Demonstrated a dose-dependent reduction of HBV DNA in the plasma of infected mice.
分子量

581.45

Formula

C24H26BrFN4O5S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

HEC72702 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
HEC72702
目录号:
HY-123767
需求量: