1. Anti-infection
  2. Bacterial Fungal
  3. L18-MDP

L18-MDP 是胞壁酰二肽衍生物,一种抗菌剂。L18-MDP 具有抗菌活性,在细菌、真菌感染中有潜在应用。

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Custom Peptide Synthesis

L18-MDP Chemical Structure

L18-MDP Chemical Structure

CAS No. : 60398-08-5

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规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

L18-MDP is a derivative of muramyl dipeptide, an antibacterial agent. L18-MDP has antibacterial activity and has potential applications in bacterial and fungal infections[1].

体内研究
(In Vivo)

L18-MDP (100 µg;皮下注射;单剂量) 在感染大肠杆菌或克雷白氏肺炎杆菌的小鼠中具有抗感染作用[1]
L18-MDP (100 µg 或 1000 µg;皮下注射、腹腔注射、静脉注射或口服;单剂量) 提高了感染大肠杆菌小鼠的存活率,改善了感染李斯特菌的小鼠病理组织[1]
L18-MDP (100 µg 或 200 µg 皮下注射或腹腔注射;一天一次持续 3 天) 提高了感染白色念珠菌小鼠的存活率[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice infected with Escherichia coli, Klebsiella pneumoniae or Listeria monocytogenes[1].
Dosage: 100 µg or 1000 µg.
Administration: Subcutaneous injection, intraperitoneal injection, intravenous injection or oral gavage; single dose.
Result: Strengthened the phagocytosis of the microorganisms, weakened the virus activity, increased the survival rate and improved the pathological tissue.
Animal Model: Mice infected with Candida albicans[1].
Dosage: 100 µg or 200 µg.
Administration: Subcutaneous injection or intraperitoneal injection; once daily for 3 days.
Result: Strengthened the phagocytosis of the microorganisms, weakened the virus activity, increased the survival rate and improved the pathological tissue.
分子量

758.94

Formula

C37H66N4O12

CAS 号
Sequence

Ac-(6-O-stearoyl)-muramyl-Ala-{d-Glu}-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

L18-MDP 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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L18-MDP
目录号:
HY-148690
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