2. Metabolic Enzyme/Protease
  3. Drug Metabolite Endogenous Metabolite
  4. Leukotriene D4-d5

Leukotriene D4-d5 

目录号: HY-113456S 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Leukotriene D4-d5 是 Leukotriene D4 的氘代物。Leukotriene D4 是由 γ-谷氨酰转肽酶代谢 LTC4 产生的过敏反应的慢反应物质 (SRS-A) 的成分之一。Leukotriene D4 是 LTC4 的第一个半胱氨酸-白三烯代谢产物。Leukotriene D4 诱导的支气管收缩和增强的血管通透性有助于哮喘的发病机理和急性超敏反应。

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Leukotriene D4-d<sub>5</sub> Chemical Structure

Leukotriene D4-d5 Chemical Structure

CAS No. : 1240398-17-7

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规格 价格 是否有货 数量
25μg（199.33 μM * 250 μL in Ethanol） ￥9900
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Leukotriene D4-d5 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Leukotriene D4-d5 is the deuterium labeled Leukotriene D4. Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Leukotriene D4-d5 相关抗体:
分子量

501.69

Formula

C25H35D5N2O6S
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Solution, -20°C, 2 years
纯度 & 产品资料

纯度: ≥98.0%

COA (258 KB)

产品使用指南 (1538 KB)
参考文献

Leukotriene D4-d5 相关分类

  • 摩尔计算器

  • 稀释计算器

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Keywords:

Leukotriene D4-d51240398-17-7Drug MetaboliteEndogenous MetaboliteInhibitorinhibitorinhibit

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