2. Anti-infection
  3. Bacterial Antibiotic
  4. LFF-571

LFF-571 是一种具有口服活性的半合成三肽抗生素。LFF-571 有效抑制 Clostridium difficile 和 Staphylococcus aureus，MIC 值分别为 0.03 和 0.125 μg/mL。LFF-571 可用于感染的研究。

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LFF-571 Chemical Structure

LFF-571 Chemical Structure

CAS No. : 1160959-55-6

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LFF-571 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LFF-571 is an orally active semisynthetic thiopeptide antibiotic. LFF-571 shows potent activity against a Clostridium difficile and Staphylococcus aureus with MIC values of 0.03 and 0.125 μg/mL, respectively. LFF-571 can be used for the research of infection[1].

体外研究
(In Vitro)

LFF-571 (0-32 μg/mL) shows MIC values of ＜0.06, ＜0.06, 0.125, 1 and 0.03 μg/mL for E. faecails, E. feacium, S. aureus, S. pyogenes and C. difficile, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

LFF-571 相关抗体:
体内研究
(In Vivo)

LFF-571 (2 and 20 mg/kg; p.o. once daily for 5 days) survives infection hamster[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Golden Syrian hamster with C. difficile infection[1]
Dosage: 2 and 20 mg/kg
Administration: Oral gavage; 2 and 20 mg/kg once daily for 5 days
Result: Showed a dose-dependent effect on survival of infection hamster.
Clinical Trial
分子量

1366.61

Formula

C60H63N13O13S6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LFF-571 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LFF-5711160959-55-6LFF571LFF 571BacterialAntibioticcarbocyclicinfectionthiopeptideS. aureusC. difficilehamsterInhibitorinhibitorinhibit

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产品名称：
LFF-571
目录号：
HY-19906
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