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  3. Lilotomab

Lilotomab  (Synonyms: HH1)

目录号: HY-P99707 纯度: 98.99%
COA

Lilotomab (HH1) 是一种鼠类抗 CD37 单克隆抗体。Lilotomab 降低克隆形成存活率。Lilotomab 具有抗肿瘤活性。

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Lilotomab Chemical Structure

Lilotomab Chemical Structure

CAS No. : 1453362-55-4

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lilotomab (HH1) is a murine anti-CD37 monoclonal antibody. Lilotomab reduces clonogenic survival. Lilotomab shows anti-tumor activity[1].

同型

Mouse IgG1 kappa

推荐同型对照抗体
种属

Mouse

IC50 & Target

CD37[1]

体外研究
(In Vitro)

Lilotomab (0-40 µg/mL; 12 days) 降低 DOHH2 和 Ramos 细胞的克隆形成存活率[1]
Lilotomab (40 µg/mL; 18 h) 诱导 DOHH2 细胞轻微凋亡[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[1]

Cell Line: Ramos, DOHH2, Rec-1 cells
Concentration: 40 µg/mL
Incubation Time: 18 h
Result: Induced apoptosis in DOHH2 cells.
体内研究
(In Vivo)

Lilotomab (0.5 mg/kg;i.v.;一次) 抑制小鼠肿瘤生长[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: SCID mice (DOHH2 cell xenografts)[1]
Dosage: 0.5 mg/kg
Administration: I.v.; once
Result: Inhibited tumor growth and increased mouse survival.
Clinical Trial
CAS 号
Unlabeled Cas

性状

液体

颜色

Colorless to light yellow

中文名称

利洛托单抗

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Lilotomab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Lilotomab
目录号:
HY-P99707
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