1. Metabolic Enzyme/Protease
  2. Mitochondrial Metabolism
  3. Malonyl CoA lithium

Malonyl CoA lithium  (Synonyms: Malonyl coenzyme A lithium)

目录号: HY-136408 纯度: ≥90.0%
COA 产品使用指南

Malonyl CoA (Malonyl Coenzyme A) lithium 是肉碱棕榈酰转移酶 1 (CPT1) 的抑制剂。高浓度的 Malonyl CoA lithium 能抑制脂肪酸氧化,而低浓度的 Malonyl CoA lithium 能允许脂肪氧化。

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Malonyl CoA lithium Chemical Structure

Malonyl CoA lithium Chemical Structure

CAS No. : 108347-84-8

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Other Forms of Malonyl CoA lithium:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Malonyl CoA (Malonyl Coenzyme A) lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation[1].

IC50 & Target

Carnitine palmitoyl transferase 1 (CPT1)[1]

体外研究
(In Vitro)

肌管与 Malonyl CoA lithium (与多胺载体)孵育可防止胰岛素刺激的葡萄糖运输,还可抑制棕榈酸盐氧化[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Myotubes
Concentration: 10 μM
Incubation Time: 30 min
Result: Prevented insulin-stimulated glucose transport and inhibited palmitate oxidation.
Formula

C24H38N7O19P3S.xLi

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

PBS 中的溶解度 : 10 mg/mL (adjust pH to 7.2)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥90.0%

参考文献

Malonyl CoA lithium 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Malonyl CoA lithium
目录号:
HY-136408
需求量: