2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. Methylene Violet 3RAX

Methylene Violet 3RAX 是一种吩嗪染料，用于染色细胞的线粒体。Methylene Violet 3RAX 可以改变DNA的分子结构，破坏DNA的模块，诱导活性单线态氧的产生。Methylene Violet 3RAX 对人红细胞 AChE 和人血浆 BChE 具有抑制作用，Kis 分别为 1.58 和 0.51 μM。Methylene Violet 3RAX 具有研究PDT (光动力疗法) 中线粒体靶向作用的潜在光敏剂的潜力。

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Methylene Violet 3RAX Chemical Structure

Methylene Violet 3RAX Chemical Structure

CAS No. : 4569-86-2

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Methylene Violet 3RAX 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

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AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an Kis of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy)[1][2].

IC50 & Target[2]

BChE

0.51 μM (Ki)

AChE

1.58 μM (Ki)

体外研究
(In Vitro)

Methylene Violet 3RAX shows antitumor activity by cutting off DNA strands in tumour cell[1]. Methylene Violet 3RAX (0-400 µM) significantly enhances cleavage of DNA with over 60% photocleavage activity towards DNA at 300 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Methylene Violet 3RAX 相关抗体:
分子量

378.90

Formula

C22H23ClN4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Methylene Violet 3RAX 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methylene Violet 3RAX4569-86-2Cholinesterase (ChE)photodynamic therapyantitumorphotosensitizerscleavage of DNAInhibitorinhibitorinhibit

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