1. Epigenetics
  2. METTL3
  3. METTL3-IN-3

METTL3-IN-1 (化合物 11) 是一种多杂环化合物,是 METTL3 的抑制剂。

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METTL3-IN-3 Chemical Structure

METTL3-IN-3 Chemical Structure

CAS No. : 2767003-71-2

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

METTL3-IN-3 (compound 11) is a polyheterocyclic compound, acts as METTL3 inhibitor[1].

IC50 & Target

METTL3[1]

体外研究
(In Vitro)

METTL3,即甲基转移酶样 3,是 N6-甲基腺苷 (m6A) 唯一的催化亚基。METTL3 参与真核 mRNA 中内部腺苷残基的转录后甲基化,形成 m6A。m6A 是最丰富的 mRNA 修饰,因此 METTL3 在多种癌症类型中发挥关键作用,或依赖于或不依赖于其 m6A RNA 甲基转移酶活性[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

555.44

Formula

C26H28BrFN6O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

METTL3-IN-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
METTL3-IN-3
目录号:
HY-148469
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