2. GPCR/G Protein NF-κB MAPK/ERK Pathway Stem Cell/Wnt
  3. NF-κB P2Y Receptor ERK
  4. MRS2693 trisodium

MRS2693 trisodium 是一种选择性的 P2Y6 激动剂，EC50 值为 0.015 μM。MRS2693 trisodium 通过减弱 NF-kappaB 的活化，激活 ERK1/2 通路，对小鼠后肢骨骼肌缺血再灌注损伤模型有细胞保护作用。

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MRS2693 trisodium Chemical Structure

MRS2693 trisodium Chemical Structure

CAS No. : 1448858-83-0

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MRS2693 trisodium 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MRS2693 trisodium is a selective P2Y6 agonist with an EC50 value of 0.015 μM. MRS2693 trisodium can reduce the activation of NF-kappaB and activate the ERK1/2 pathway, and has a cytoprotective effect on mouse hindlimb skeletal muscle ischemia-reperfusion injury model[1][2].

分子量

596.00

Formula

C9H10IN2Na3O12P2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MRS2693 trisodium 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MRS2693 trisodium1448858-83-0NF-κBP2Y ReceptorERKNuclear factor-κBNuclear factor-kappaBExtracellular signal regulated kinasesP2Y6AD293HCT116C2C12Inhibitorinhibitorinhibit

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