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  4. Natalizumab (Solution)

Natalizumab (Solution) 

目录号: HY-108831A 纯度: 98.72%
COA

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Natalizumab (Solution) 是一种重组的人源化 IgG4 单克隆抗体，与 α4β1-整联蛋白 (α4β1-integrin) 结合并阻断其与血管细胞粘附分子 1 (VCAM-1) 的相互作用。Natalizumab 可用于复发缓解型多发性硬化症和克罗恩氏病的研究。Natalizumab 也可阻止淋巴细胞进入中枢神经系统，从而防止急性脱髓鞘复发。

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Natalizumab (Solution) Chemical Structure

Natalizumab (Solution) Chemical Structure

CAS No. : 189261-10-7

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规格 价格 是否有货 数量
1 mg ￥1900
In-stock
5 mg ￥4600
In-stock
10 mg ￥7400
In-stock
25 mg ￥9800
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Other Forms of Natalizumab (Solution):

Natalizumab (Solution) 相关抗体

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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生物活性

Natalizumab (Solution) is a recombinant, humanized IgG4 monoclonal antibody, binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses[1].

同型

Human IgG4 kappa
推荐同型对照抗体
种属

Humanized
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 98.72%

COA (151 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Natalizumab (Solution) 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Natalizumab (Solution)189261-10-7IntegrinrecombinantIgG4 monoclonal antibodyintegrinVCAM-1relapsing remitting multiple sclerosisCrohn's diseaseInhibitorinhibitorinhibit

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