2. Epigenetics
  3. Histone Acetyltransferase
  4. NSC 698600

NSC 698600 是一种有效的 PCAF 抑制剂，其 IC50 值为 6.51 µM (PCAF/H31-21)。NSC 698600 具有较好的抗癌活性，能抑制癌细胞的增殖。

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NSC 698600 Chemical Structure

NSC 698600 Chemical Structure

CAS No. : 908069-17-0

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NSC 698600 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NSC 698600 is a potent PCAF inhibitor, with IC50 of 6.51 µM (PCAF/H31-21). NSC 698600 exhibits good activity of inhibiting the proliferation of cancer cells[1].

IC50 & Target

IC50: 6.51 µM (PCAF/H31-21)[1].
体外研究
(In Vitro)

NSC 698600 (25 µM; 72 h) exhibits antiproliferative effect to SK-N-SH and HCT116 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

NSC 698600 相关抗体:

Cell Proliferation Assay[1]

Cell Line: SK-N-SH, HCT116 cells
Concentration: 25 µM
Incubation Time: 72 h
Result: Showed antiproliferative effect to SK-N-SH and HCT116 cells with GI50 of 12.2 µM and growth inhibition of 40%, respectively.
分子量

272.32

Formula

C14H12N2O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NSC 698600 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NSC 698600908069-17-0NSC698600NSC-698600Histone AcetyltransferaseHATsHATPCAFpyridoisothiazolonesHAT inhibitorcancerSK-N-SHHCT116Inhibitorinhibitorinhibit

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目录号：
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